Biotechnology and Bioengineering

Biotechnology and Bioengineering News -- ScienceDaily Biotechnology and bioengineering research news.

  • Biological signalling processes in intelligent materials
    on July 18, 2018 at 2:48 pm

    Researchers are developing innovative biohybrid systems with information processing functionality. […]

  • Researchers decode molecule that gives living tissues their flexibility
    on June 25, 2018 at 11:26 pm

    The stretchiness that allows living tissues to expand, contract, stretch, and bend throughout a lifetime is the result of a protein molecule called tropoelastin. Remarkably, this molecule can be stretched to eight times its length and always returns back to its original size. Now, for the first time, researchers have decoded the molecular structure of this complex molecule, as well as the details of what can go wrong with its structure in various genetically driven diseases. […]

  • Engineering bacteria to exhibit stochastic Turing patterns
    on June 21, 2018 at 4:18 pm

    A new study has brought science one step closer to a molecular-level understanding of how patterns form in living tissue. The researchers engineered bacteria that, when incubated and grown, exhibited stochastic Turing patterns: a 'lawn' of synthesized bacteria in a petri dish fluoresced an irregular pattern of red polka dots on a field of green. […]

  • Rewiring plant defense genes to reduce crop waste
    on June 20, 2018 at 8:24 pm

    Plants could be genetically rewired to better resist disease, helping safeguard crop yields worldwide according to new research. Defensive feedback control system developed enables plants to strengthen their defenses to withstand attack by re-wiring existing gene connections. The system uses same approach as aircraft autopilots use to counteract turbulence. […]

  • Genetic engineering researcher: Politicians are deaf to people's ethical concerns
    on June 15, 2018 at 10:54 pm

    A new study reports that political discussions about genetically modified foods have ignored concerns among Danes that GM foods are 'unnatural'. […]

  • Gene editing just got easier
    on June 8, 2018 at 12:56 pm

    Researchers have made CRISPR technology more accessible and standardized by simplifying its complex implementation in a way that offers a broad platform for off-the shelf genome engineering. […]

  • A change in bacteria's genetic code holds promise of longer-lasting drugs
    on June 4, 2018 at 3:19 pm

    By altering the genetic code in bacteria, researchers have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases. […]

  • A photosynthetic engine for artificial cells
    on May 29, 2018 at 5:20 pm

    Researchers have engineered a cell-like structure that harnesses photosynthesis to perform metabolic reactions, including energy harvesting, carbon fixation and cytoskeleton formation. […]

  • Programming synthetic molecular codes to turn genes 'on'
    on May 24, 2018 at 6:15 pm

    A team of researchers developed a synthetic molecular code to script gene activation. The process could help lead to future gene-based therapies for a wide array of diseases. […]

  • Researchers build artificial cellular compartments as molecular workshops
    on May 22, 2018 at 4:33 pm

    How to install new capabilities in cells without interfering with their metabolic processes? Scientists have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields. […]

  • Faster genome evolution methods to transform yeast
    on May 22, 2018 at 3:44 pm

    Scientists have created a new way of speeding up the genome evolution of baker's yeast Saccharomyces cerevisiae, the same yeast we use for bread and beer production. […]

  • Cocoa CRISPR: Gene editing shows promise for improving the 'chocolate tree'
    on May 10, 2018 at 2:12 pm

    Use of the powerful gene-editing tool CRISPR-Cas9 could help to breed cacao trees that exhibit desirable traits such as enhanced resistance to diseases. […]

  • Tissue-engineered human pancreatic cells successfully treat diabetic mice
    on May 8, 2018 at 3:17 pm

    Researchers tissue-engineered human pancreatic islets in a laboratory that develop a circulatory system, secrete hormones like insulin and successfully treat sudden-onset type 1 diabetes in transplanted mice. The scientists use a new bioengineering process they developed called a self-condensation cell culture. The technology helps nudge medical science closer to one day growing human organ tissues from a person's own cells for regenerative therapy, say study investigators. […]

  • CRISPR/Cas9 silences gene associated with high cholesterol
    on April 26, 2018 at 4:59 pm

    Biomedical engineers have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment. This marks the first time researchers have delivered CRISPR/Cas9 repressors for targeted therapeutic gene silencing in adult animal models. […]

  • Far-red fluorescent silk can kill harmful bacteria as biomedical and environmental remedy
    on April 19, 2018 at 5:10 pm

    A silk hybrid material attacks bacteria when illuminated by a green light, thanks to a far-red fluorescent protein researchers transferred to its genetic makeup. […]

  • Breakthrough brings gene-editing medicine one step closer to patient applications
    on April 13, 2018 at 6:45 pm

    Researchers have discovered a way to greatly improve the accuracy of gene-editing technology by replacing the natural guide molecule it uses with a synthetic one called a bridged nucleic acid, or BNA. The research promises to bring the technology much closer to therapeutic reality. […]

  • Pig model of Huntington's offers advantages for testing treatments
    on March 29, 2018 at 6:10 pm

    A team of scientists has established a 'knock in' pig model of Huntington's disease (HD), an inherited neurodegenerative disease, anticipated to be useful for testing treatments. […]

  • Let them eat xylose: Yeast engineered to grow efficiently on novel nutrients
    on March 26, 2018 at 1:03 pm

    Researchers have created a genetically modified yeast that can more efficiently consume a novel nutrient, xylose, enabling the yeast to grow faster and to higher cell densities, raising the prospect of a significantly faster path toward the design of new synthetic organisms for industrial applications, according to a new study. […]

  • New innovations in cell-free biotechnology
    on March 23, 2018 at 5:27 pm

    A new platform to conduct cell-free protein synthesis could lead to improved quality of manufactured protein therapeutics and biomaterials. […]

  • Using light to turn yeast into biochemical factories
    on March 22, 2018 at 10:13 pm

    Researchers have used a combination of light and genetic engineering to controlling the metabolism, or basic chemical process, of a living cell. Building on techniques that already have transformed the field of neuroscience, the researchers used light to control genetically-modified yeast and increase its output of commercially valuable chemicals. […]

  • Making intricate images with bacterial communities
    on March 19, 2018 at 11:00 pm

    A technique for growing sticky films of bacteria into elaborate microscopic images could reveal how potentially dangerous biofilms grow and transmit antibiotic resistance, and could lead to novel biomaterials or synthetic microbial communities. […]

  • Engineers create most efficient red light-activated optogenetic switch for mammalian cells
    on March 13, 2018 at 12:41 pm

    Researchers have developed a light-activated switch that can turn genes on and off in mammalian cells. This is the most efficient so-called 'optogenetic switch' activated by red and far-red light that has been successfully designed and tested in animal cells -- and it doesn't require the addition of sensing molecules from outside the cells. […]

  • Gene knockout using new CRISPR tool makes mosquitoes highly resistant to malaria parasite
    on March 8, 2018 at 7:30 pm

    Deleting a single gene from mosquitoes can make them highly resistant to the malaria parasite and thus much less likely to transmit the parasite to humans, according to a new article. […]

  • Bioengineering team's 'circuit' work may benefit gene therapy
    on March 6, 2018 at 4:57 pm

    Researchers have designed genetic 'circuits' out of living cellular material in order to gain a better understanding of how proteins function, with the goal of making improvements. […]

  • Drug-producing bacteria possible with synthetic biology breakthrough
    on March 5, 2018 at 6:04 pm

    Bacteria could be programmed to efficiently produce drugs, thanks to breakthrough research into synthetic biology using engineering principles. […]

  • Mitochondria-to-nucleus messenger protein discovered
    on March 1, 2018 at 7:41 pm

    Researchers have identified a protein, G-Protein Pathway Suppressor 2 (GPS2), that moves from a cell's mitochondria to its nucleus in response to stress and during the differentiation of fat cells. While proteins with similar functions had previously been found in yeast and worms, this is first direct messenger discovered in the cells of mammals. […]

  • Scientists improve DNA transfer in gene therapy
    on February 15, 2018 at 3:57 pm

    Parkinson's disease, Huntington's disease, cystic fibrosis - these and many other fatal hereditary human diseases are genetically transmitted. Many cancers and cardiovascular diseases are also caused by genetic defects. Gene therapy is a promising possibility for the treatment of these diseases. With the help of genetically modified viruses, DNA is introduced into cells in order to repair or replace defective genes. By using this method, scientists have discovered a quicker and more efficient treatment for the cells. […]

  • Mouse study adds to evidence linking gut bacteria and obesity
    on February 12, 2018 at 3:06 pm

    A new study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome -- a 'garden' of bacterial, viral and fungal genes -- plays a substantial role in the development of obesity and insulin resistance in mammals, including humans. […]

  • Efficient technique discovered for isolating embryonic stem cells in cows
    on February 9, 2018 at 10:05 pm

    Scientists have developed a highly efficient method of isolating embryonic stem cells in cows. Producing embryonic stem cells from large livestock species like cattle is important for genetic testing, genome engineering, and studying human disease. […]

  • Workbench for virus design
    on February 6, 2018 at 3:03 pm

    Researchers have developed a technology platform that allows them to systematically modify and customize bacteriophages. This technology is a step towards making phage therapies a powerful tool for combating dangerous pathogens. […]